Liquid Chromatography Simulation
An Exponentially Modified Gaussian Function (EMG ) is used here to simulate the elution profile of analytes off a stationary phase column. Key features of the EMG is its ability to produce tailing peaks.
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Function argument t is time, with gradient parameter G, and parameters h, tR, tao, and sigma, each functions of pH and Injection Volume.
Click the button below to edit method parameters Mobile Phase pH and Injection Volume and generate the elution simulation under the defined conditions.
Derivation of the featured EMG model by taking a convolution (sum of pairwise products) of a Gaussian and exponential function.
Example data used to validate the EMG model under variations in input parameters pH and injection volume.
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